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Axitinib Sulfoxide

metabolite reference standard

CAS1347304-18-0
Axitinib Sulfoxide chemical structure
Cat. no. A794885 Purity HPLC Form Light Yellow Solid

Specifications

Product name
Axitinib Sulfoxide
CAS number
1347304-18-0
Catalogue number
A794885
Molecular formula
C22 H18 N4 O2 S
Molecular weight
402.47
Purity (HPLC)
Physical form
Light Yellow Solid
Storage
4 °C
SMILES
CNC(=O)c1ccccc1S(=O)c2ccc3c(\C=C\c4ccccn4)n[nH]c3c2
Available pack sizes
Quoted on request
Lead time
In stock
Intended use
Related substances and impurity testing, method development and validation, system suitability, QC release and stability testing; metabolite identification and bioanalytical methods.

Fields shown as — are not published for this item. They are left blank rather than filled with an estimate.

Description

Axitinib Sulfoxide (CAS 1347304-18-0) is supplied by ImpurityLab as a metabolite standard, used as a reference for metabolite identification and for bioanalytical methods. Catalogue number A794885. It is related to Axitinib.

Parent drug substance. Axitinib. Browse the full Axitinib impurity and related compound standards held by ImpurityLab.

The material is issued against molecular formula C22 H18 N4 O2 S, molecular weight 402.47 g mol−1, physical form described as light yellow solid.

Structural notation: CNC(=O)c1ccccc1S(=O)c2ccc3c(\C=C\c4ccccn4)n[nH]c3c2

Reported solubility: DMSO (Slightly), Methanol (Slightly, Heated)

Metabolites are used to confirm structure assignments in metabolism studies and as calibrants in bioanalytical methods. They are not pharmacopoeially lettered impurities, so the acceptance criterion comes from your own study rather than from a monograph.

Storage. Store at 4 °C. Allow the container to reach room temperature before opening so that moisture does not condense onto the material. Record the date of first opening on the label.

Pack sizes. Quoted on request. Non-standard quantities are quoted on request, normally within two working days.

Documentation. Each lot is released with a certificate of analysis that states the assay method, the water content and the form as supplied. The safety data sheet is available with the same lot number. Quote catalogue number A794885 when requesting either document.

Documentation

Certificate of analysis (per lot)COA-A794885Download
Safety data sheet (SDS)SDS-A794885Download

Documents are issued per lot. The COA you receive describes the lot that ships, not a representative sample.

Regulatory reference

Metabolite reference standard used for metabolite identification and bioanalytical method support. Not a pharmacopoeially lettered impurity.

References are provided to help you map a standard to a pharmacopoeial method. Confirm the acceptance criteria against your own method before use.

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